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Coptisine

SKU: orb1301355

Description

Coptisine is a bioactive alkaloid with research applications in cardioprotection, oncology, and metabolic studies. It demonstrates anti-apoptotic and anti-inflammatory effects in myocardial ischemia-reperfusion models and exhibits anti-metastatic activity in breast cancer cell lines like MDA-MB-231 by modulating MMP-9 and TIMP-1.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number3486-66-6
MW320.32
Purity99.91% (May vary between batches)
FormulaC19H14NO4
SMILESC1=2C=3C(=CC4=C(C3)OCO4)CC[N+]1=CC=5C(C2)=CC=C6C5OCO6
TargetLDLR,IDO,Indoleamine 2,3-Dioxygenase (IDO)
SolubilityDMSO:3.91 mg/mL (12.21 mM)

Bioactivity

Target IC50
IDO:6.3 μM.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Coptisin, Coptisine, Inhibitor, inhibit, Indoleamine 2,3-Dioxygenase (IDO), Indoleamine 2,3Dioxygenase (IDO), Indoleamine2,3Dioxygenase, Indoleamine2,3Dioxygenase(IDO), Indoleamine 2,3-Dioxygenase, IDO

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 130.00
1 ml x 10 mM (in DMSO)
$ 150.00
10 mg
$ 180.00
25 mg
$ 310.00
50 mg
$ 520.00
100 mg
$ 740.00
DispatchUsually dispatched within 5-10 working days
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