Coptisine sulfate

SKU: orb1302372

Description

Coptisine sulfate is a bioactive alkaloid salt that demonstrates growth-inhibitory effects on human cancer cell lines, as identified in the NCI's anticancer screening program. It is utilized in oncology research for in vitro cytotoxicity studies and in vivo pharmacological investigations of its potential chemotherapeutic mechanisms.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1198398-71-8
• MW: 417.39
• Purity: 99.36%
• Formula: C₁₉H₁₄NO₄.HO₄S
• SMILES: OS([O-])(=O)=O.C1Oc2cc3CC[n+]4cc5c6OCOc6ccc5cc4-c3cc2O1
• Target: Indoleamine 2,3-Dioxygenase (IDO),IDO
• Solubility: Ethanol:Soluble;DMSO:Slightly soluble;Pyridine, Methanol, etc.:Soluble

Bioactivity

• Target IC50:
  IDO:5.8 μM (Ki)|IDO:6.3 μM (IC50)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Indoleamine2,3Dioxygenase(IDO), Indoleamine2,3Dioxygenase, Indoleamine 2,3-Dioxygenase (IDO), Indoleamine 2,3-Dioxygenase, Indoleamine 2,3Dioxygenase (IDO), IDO, Coptisine, Coptisine sulfate, Coptisine Sulfate

Compound Identifiers

PubChem CID

131674029