CNOT3 (N) Antibody, Rabbit Polyclonal

SKU: orb131857

Description

Rabbit polyclonal to CNOT3. CCR4-NOT transcription complex subunit 3 (CNOT3) belongs to the CNOT2/3/5 family. CNOT3 is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. CNOT3 may be involved in metabolic regulation; additionally, CNOT3 may also be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism.

Images & Validation

• Tested Applications: WB
• Dilution range: WB:1:1000-1:3000
• Reactivity: Human, Mouse
• Application Notes:
  WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human CNOT3.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human CNOT3
• Molecular Weight: 82
• Purity: Affinity purification

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Disclaimer: For research use only

Alternative Names

anti CCR4-NOT transcription complex subunit 3 antibody, anti CCR4-associated factor 3 antibody, anti Leukocyte receptor cluster member 2 antibody, anti KIAA0691 antibody, anti LENG2 antibody, anti NOT3 antibody

Quick Database Links

UniProt

O75175