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Clopidogrel

SKU: orb1226936

Description

A thienopyridine-class antiplatelet agent that works by irreversibly inhibiting P2Y12 receptor on platelets; used to reduce the risk of heart disease and stroke in those at high risk.Thrombosis Approved(In Vivo):Clopidogrel, administered during the last three months, significantly decreases blood glucose, collagen and fibronectin expression compared to vehicle-treated diabetic mice. Clopidogrel markedly ameliorates hyperglycemia-induced renal fibrosis. The combination therapy of clopidogrel and aspirin (dual-antiplatelet therapy) has been shown to be significantly beneficial compared to aspirin monotherapy and has also shown to decrease sub-acute stent thrombosis as well as recurrent ischemic events following ACS.

Images & Validation

Key Properties

CAS Number113665-84-2
MW321.8217
Purity>98% (HPLC)
FormulaC16H16ClNO2S
SMILESCOC(=O)[C@H](C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3
TargetP2Y Receptor
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Clopidogrel (orb1226936)

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