Clioquinol

SKU: orb1226587

Description

Clioquinol(Iodochlorhydroxyquin) is an antifungal drug and antiprotozoal compound that shows effectivity for Alzheimer's disease treatment and induce Y cell death.(In Vitro):Clioquinol (0.01-1000 uM; 72 hours) shows anticancer activity against U251, and MV-4-11 cells.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 130-26-7
• MW: 305.5
• Purity: >98% (HPLC)
• Formula: C₉H₅ClINO
• SMILES: OC1=C2N=CC=CC2=C(Cl)C=C1I
• Target: Others
• Solubility: Chloroform: 15mg/mL

Bioactivity

• In Vitro:
  Clioquinol (0.01-1000 uM; 72 hours) shows anticancer activity against U251, and MV-4-11 cells. Cell Viability Assay Cell line: The MV-4-11, and U-251 cell lines. Concentration: 0.01, 0.1, 1, 10, 100, 1000 uM Incubation time: 72 hours. Result: The IC50s were 32 and 46 μM in U251 and MV-4-11 cells, respectively.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Iodochlorohydroxyquin | NSC 3531 | NSC 74938

Quick Database Links

Gene Symbol

Others