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Catalog Number | orb1726564 |
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Category | Antibodies |
Description | Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis). |
Species/Host | Rabbit |
Clonality | Recombinant |
Tested applications | FC, ICC, IHC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | A synthesized peptide derived from human CLIC4 |
Antibody Type | Recombinant Antibody |
Dilution range | WB:1:500~1:2000IHC:1:50~1:200ICC/IF:1:50~1:200IP:1:50FC:1:50 |
Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Conjugation | Unconjugated |
MW | 29kDa |
UniProt ID | Q9Y696 |
Source | Recombinant Rabbit |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Alternative names | Chloride intracellular channel 4; Clic4; CLIC4L; H Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Western blot analysis of CLIC4 expression in 293 cell lysate.