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CK 869

SKU: orb1225133

Description

CK 869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, inhibits actin polymerization (IC50=11 uM); does not inhibit budding or fission yeast Arp2/3 complexes.

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Key Properties

CAS Number388592-44-7
MW394.283
Purity>98% (HPLC)
FormulaC17H16BrNO3S
SMILESO=C1N(C2=CC=C(OC)C=C2OC)C(C3=CC=CC(Br)=C3)SC1
TargetArp2/3 complex
SolubilityDMS : 75 mg/mL 190.22 mM; H2O : < 0.1 mg/mL

Bioactivity

In Vitro
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM. CK-869 significantly inhibits MT polymerization even at a concentration of 25 μM.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CK-0157869

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Protocol Information

CK 869 (orb1225133)

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Available Sizes

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200 mg
500 mg
2 mg
$ 80.00
5 mg
$ 100.00
10 mg
$ 150.00
25 mg
$ 260.00
50 mg
$ 400.00
100 mg
$ 620.00