Cixutumumab Antibody

SKU: orb2278747

Description

Cixutumumab (IMC-A12) is a human IgG1 monoclonal antibody that binds to and blocks the insulin-like growth factor 1 receptor (IGF1R). It inhibits IGF1-mediated signaling and demonstrates antitumor activity, making it a valuable research tool for studying cancers such as non-small cell lung cancer and prostate cancer in both in vitro and in vivo models.

Research Area

Signal Transduction

Key Properties

• Antibody Type: Inhibitor Antibody
• Clonality: Monoclonal
• Target: IGF-1R
• Molecular Weight: 146.32 kDa
• Purity: 95.00% (May vary between batches)
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Concentration: 7.13 mg/mL
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cixutumumab, IMCA12, IMC-A12, NSC 742460, LY 3012217, LY3012217, NSC742460, NSC-742460, IGF1R, IGF-1R

Quick Database Links

Gene Symbol

IGF-1R