CIL56

• Catalog Number: orb1302964
• Category: Small Molecules
• Description: CIL56
• CAS Number: 300802-28-2
• Purity: 99.91%
• MW: 489.61
• SMILES: N(O)=C1C=2C(C=3C1=CC(S(=O)(=O)N4CCCCC4)=CC3)=CC=C(S(=O)(=O)N5CCCCC5)C2
• Formula: C₂₃H₂₇N₃O₅S₂
• Biological Activity: CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated, monounsaturated, and polyunsaturated fatty acids in HT-1080 cells in vitro.HT-1080 cells lacking acetyl-CoA carboxylase 1 (ACC1), the rate-limiting enzyme in fatty acid synthesis, exhibit 5-fold resistance to CIL56 treatment, indicating ACC1 activity sensitizes cells to CIL56-induced cell death.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.