Cichoric Acid

SKU: orb1297661

Description

Cichoric Acid (Dicaffeoyltartaric acid) is a bioactive compound that potently inhibits HIV-1 integrase and viral replication in tissue-based assays. It also exhibits cannabinomimetic properties, acting through both CB2 receptor-dependent and independent pathways. This small molecule is utilized in virology and immunology research, including in vitro studies on integrase function and inflammation.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 6537-80-0
• MW: 474.37
• Purity: 98.57% (May vary between batches)
• Formula: C₂₂H₁₈O₁₂
• SMILES: OC(=O)[C@H](OC(=O)\C=C\c1ccc(O)c(O)c1)[C@@H](OC(=O)\C=C\c1ccc(O)c(O)c1)C(O)=O
• Target: Reactive Oxygen Species|||HIV Protease
• Solubility: H2O:5 mg/mL (10.54 mM);DMSO:347 mg/mL (731.5 mM);50% PEG300+50% Saline:10 mg/mL (21.08 mM)

Bioactivity

• Target IC50:
  HIV-1 integrase:0.8 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-inflammatory, antidiabetic, antioxidant, Apoptosis, Cichoric Acid, Chicoric Acid, Dicaffeoyltartaric acid, insulin resistance, Inhibitor, HIVProtease, HIV-I integrase, HIV Protease, MAPK, glucosamine, glucose uptake, p-Akt, mitochondria, inhibit, Reactive Oxygen Species, PI3K/Akt, ReactiveOxygenSpecies, ROS

Compound Identifiers

PubChem CID

5281764