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ChX710

SKU: orb1218297

Description

ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.

Images & Validation

Key Properties

CAS Number2438721-44-7
MW323.39
Purity>98% (HPLC)
FormulaC18H21N5O
SMILESO=C(NC(C)CN(C)C)C1=C(N=C(C2=CC=NC=C2)N3)C3=CC=C1
TargetSTING
SolubilityDMSO:20 mg/mL (61.84 mM; Need ultrasonic)

Bioactivity

In Vitro
ChX710 treatment is found to efficiently prime the cellular response to DNA transfection via STING as assessed by strong synergistic effects on IFN-β expression at both transcriptional and protein levels.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

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2 mg
$ 220.00
5 mg
$ 320.00
10 mg
$ 470.00
25 mg
$ 840.00
50 mg
$ 1,210.00
100 mg
$ 1,680.00
500 mg
$ 3,340.00