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Chromogranin A Antibody

Catalog Number: orb386168

DispatchUsually dispatched within 5-10 working days
$ 764.00
Catalog Numberorb386168
CategoryAntibodies
DescriptionChromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Species/HostRabbit
ClonalityRecombinant
Clone NumberCHGA/1773R
Tested applicationsIHC-P
ReactivityHuman
IsotypeRabbit IgG, kappa
ImmunogenRecombinant human protein was used as the immunogen for the recombinant Chromogranin A antibody.
Dilution rangeImmunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT
PurityProtein A affinity chromatography
ConjugationUnconjugated
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Hazard InformationThis recombinant Chromogranin A antibody is available for research use only.
UniProt IDP10645
StorageStore the recombinant Chromogranin A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
NoteFor research use only
Application notesOptimal dilution of the recombinant Chromogranin A antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Expiration Date12 months from date of receipt.
Chromogranin A Antibody

Immunohistochemical staining of Human parathyroid gland using Chromogranin A antibody

Chromogranin A Antibody

Immunohistochemical staining of Human pancreas using Chromogranin A antibody

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    ELISA,  FC,  IHC,  WB

    Human

    Rabbit

    Polyclonal

    Unconjugated

    10 μg, 100 μg
  • CHGA Antibody [orb1247992]

    ELISA,  FC,  IHC,  WB

    Human

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    Polyclonal

    Unconjugated

    0.1 mg
  • CHGA Antibody [orb1252582]

    FC,  IF,  IHC-P

    Human, Rat

    Mouse

    Monoclonal

    Unconjugated

    100 μg
  • NSE Antibody / Neuron Specific Enolase [orb386134]

    IHC-P,  WB

    Human, Mouse, Rat

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg
  • CHGA antibody [orb387980]

    IHC-P

    Human, Mouse, Rat

    Mouse

    Monoclonal

    Unconjugated

    100 μg, 20 μg
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