Chromium picolinate

SKU: orb1302744

Description

Chromium picolinate

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 14639-25-9
• MW: 418.30
• Purity: 99.64%
• Formula: C₁₈H₁₂CrN₃O₆
• SMILES: O=C1[O-][Cr+3]23([N]=4C(C(=O)[O-]2)=CC=CC4)([N]=5C(C(=O)[O-]3)=CC=CC5)[N]=6C1=CC=CC6
• Target: Apoptosis,DNA,p38 MAPK
• Solubility: DMSO:4.19 mg/mL (10.02 mM)

Bioactivity

• In Vivo:
  Acrivastine (usually 8mg three times daily) is an effective and well-tolerated antihistamine in the treatment of chronic urticaria and allergic rhinitis. Acrivastine causes less drowsiness than clemastine, the incidence of adverse effects being indistinguishable from that with placebo or terfenadine. In the treatment of dermatoses in which histamine has a pathogenetic role, the efficacy of acrivastine is superior to that of placebo and similar to that of usual dosages of clemastine, hydroxyzine, chlorpheniramine, cyproheptadine or terfenadine . Both 4 mg and 8 mg acrivastine alleviate the symptoms of seasonal allergic rhinitis with significant improvements in the symptom scores for sneezing, running nose and the calculated overall score. In addition, 8 mg acrivastine reduces the symptom scores for watery eyes and itchy throat. Acrivastine is both well tolerated and effective in the treatment of seasonal allergic rhinitis .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Cr(Pic)3, DNA mutation, Chromium picolinate, Chromium (III) picolinate, p38 MAPK, p38, p38MAPK

Compound Identifiers

PubChem CID

56840998