CHEK2 Antibody (N-term)

SKU: orb35291

Description

Peptide affinity purified rabbit polyclonal antibody.

Research Area

Cell Biology

Images & Validation

• Tested Applications: FC, IF, IHC-P, WB
• Dilution Range: WB: 1:1000, IHC-P: 1:50-100, FACS: 1:10-50, IF/ICC: 1:10-50
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Target: CHEK2
• Molecular Weight: 60915
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-Cds1 antibody, anti-Serine/threonine-protein kinase Chk2, RAD53 antibody, anti-CHK2 antibody, anti-CHEK2 antibody

Quick Database Links

Gene Symbol

CHEK2

UniProt

O96017

RefSeq (Protein):NP_001244316.1, NP_001005735.1, NP_009125.1, NP_665861.1

Yao, Jing et al. 53BP1 loss induces chemoresistance of colorectal cancer cells to 5-fluorouracil by inhibiting the ATM-CHK2-P53 pathway J Cancer Res Clin Oncol, 143, 419-431 (2017)

PubMed: 27838786