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Cefacetrile

SKU: orb2901262

Description

Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number10206-21-0
MW339.32
Purity>98% (HPLC)
FormulaC13H13N3O6S
SMILESC(O)(=O)C=1N2[C@@]([C@H](NC(CC#N)=O)C2=O)(SCC1COC(C)=O)[H]
TargetAntibiotic
SolubilityIn Vitro: DMSO : 100 mg/mL (294.71 mM; Ultrasonic )

Bioactivity

In Vivo
Cefacetrile (50, 100 and 500 mg/kg, s. c.) does not alter fertility, gestation and post-natal development of term foetuses of rats and fertility and gestation of rabbits. Cefacetrile (1 g/kg, i. v.) produces no nephrotoxicity in rabbits and rats.
In Vitro
Cefacetrile (less than 1 μg/mL) inhibits Staphylococcus aureusand Streptococcus pyogenes.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • Cefacetrile [orb1697927]

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    C13H13N3O6S

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Protocol Information