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CDDO-dhTFEA

SKU: orb1219050

Description

CDDO-dhTFEA is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. It restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats.

Images & Validation

Key Properties

CAS Number1191265-33-4
MW574.72
Purity>98% (HPLC)
FormulaC33H45F3N2O3
SMILESC[C@@]12CC[C@@H]3[C@@]([C@H]1CC(=O)[C@H]4[C@]2(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)NCC(F)(F)F)C)(C=C(C(=O)C3(C)C)C#N)C
TargetNF-κB
SolubilityDMSO:100 mg/mL (174.00 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

RTA dh404

Similar Products

  • CDDO-dhTFEA [orb1308849]

    99.59% (May vary between batches)

    1191265-33-4

    574.72

    C33H45F3N2O3

    5 mg, 500 mg, 2 mg, 10 mg, 25 mg, 1 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

Available Sizes

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2 mg
$ 160.00
5 mg
$ 260.00
10 mg
$ 430.00
25 mg
$ 840.00
50 mg
$ 1,200.00
100 mg
$ 1,680.00
500 mg
$ 3,330.00