CDC42 Rabbit mAb [KD Validated] Antibody

SKU: orb1951330

Description

Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.

Images & Validation

• Tested Applications: FC, IHC, IP, WB
• Dilution Range: WB 1:1000~1:2000 IHC 1:50~1:200 IP 1:30 FC 1:50
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human CDC42
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CDC42; CDC42Hs; G25K; TKS;

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of CDC42 expression in (1) Jurkat cell lysate; (2) Mouse spleen lysate.

Quick Database Links

UniProt

P60953