Cdc23/APC8 Rabbit mAb [KD Validated]

• Catalog Number: orb1951334
• Category: Antibodies
• Description: Anaphase-promoting complex subunit 8 (APC8, CDC23) is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16). APC8 protein associates with APC3 and APC6 to facilitate recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. Research studies suggest that APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth.
• Species/Host: Rabbit
• Clonality: Recombinant
• Tested applications: ICC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Cdc23/APC8
• Antibody Type: Recombinant Antibody
• Dilution range: WB 1:500~1:2000 ICC/IF 1:50~1:100
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Conjugation: Unconjugated
• UniProt ID: Q9UJX2
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of Cdc23/APC8 expression in (1) HepG2 cell lysate; (2) Jurkat cell lysate.