CD86 (N) Antibody, Mouse Monoclonal

SKU: orb66683

Description

Mouse monoclonal to CD86.T-lymphocyte activation antigen CD86 is a receptor involved in the costimulatory signal essential forT-lymphocyte proliferation and interleukin-2 production. CD86 binds to CD28 or CTLA-4 and may playa critical role in the early events of T-cell activation and costimulation of naive T-cells, such asdeciding between immunity and anergy. CD86 isoform 2 interferes with the formation of CD86 clusters,and thus acts as a negative regulator of T-cell activation.

Research Area

Epigenetics, Immunology, Infectious Diseases, Stem Cells

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Immunogen: N-terminal region of human CD86
• Molecular Weight: 38
• Purity: Caprylic Acid-Ammonium Sulfate precipitation
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.02% Thimerosal
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-Activation B7 2gen antibody, anti-Activation B7-2gen 3 antibody, anti-B lymphocyte activatio antibody, anti-B lymphocyte activationgen B72 antibody, anti-B7 2gen antibody, anti-B70 antibody, anti-B7-2 antibody, anti-BU63 antibody, anti-CD28gen ligand 2 antibody, anti-CD28LG2 antibody, anti-CD86 antibody, anti-CD86gen antibody, anti-CD86 molecule antibody, anti-FUN1 antibody, anti-LAB72 antibody, anti-MGC34413 antibody, anti-T lymphocyte activationgen CD86 antibody

Western blot analysis of total cell extracts from human Jurkat using CD86 antibody

Quick Database Links

UniProt

P42081