CD73-IN-4

SKU: orb1298279

Description

CD73-IN-4 is a potent, selective inhibitor of CD73, featuring a methylenephosphonic acid pharmacophore. This compound is a valuable research tool for investigating CD73 function in oncology and immunology, supporting both in vitro enzymatic assays and in vivo studies on tumor microenvironment and immune response modulation.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2216764-29-1
• MW: 463.81
• Purity: 98.61% (May vary between batches)
• Formula: C₁₆H₂₃ClN₅O₇P
• SMILES: O[C@H]1[C@H](N2C=3C(C=N2)=C(NC4CCCC4)N=C(Cl)N3)O[C@H](COCP(=O)(O)O)[C@H]1O
• Target: CD73
• Solubility: DMSO:125 mg/mL (269.51 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.62 mM)

Bioactivity

• Target IC50:
  CD73:2.6 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

differentiation, cluster, CD73, CD73 IN 4, CD73IN4, CD-73-IN-4, CD73-IN-4, 5'-Ribonucleotide phosphohydrolase, acid, cancer, inhibit, immunology, methylenephosphonic, Inhibitor

Compound Identifiers

PubChem CID

135348940