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Catalog Number | orb2636132 |
---|---|
Category | Antibodies |
Description | Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. |
Clonality | Recombinant |
Species/Host | Mouse |
Isotype | Mouse IgG2b, kappa |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant full-length human CD36 protein was used as the immunogen for the recombinant CD36 antibody. |
UniProt ID | P16671 |
Tested applications | IHC-P |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml |
Application notes | Optimal dilution of the recombinant CD36 antibody should be determined by the researcher. |
Antibody Type | Primary Antibody |
Clone Number | rGPIIIb/9240 |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Hazard Information | This recombinant CD36 antibody is available for research use only. |
Note | For research use only |
SDS-PAGE analysis of purified, BSA-free recombinant CD36 antibody (clone rGPIIIb/9240) as confirmation of integrity and purity.
ICC, IF, IHC-Fr, IHC-P, WB | |
Mouse, Rat | |
Human, Mouse, Rat | |
Rabbit | |
Recombinant | |
Unconjugated |
FC, IF, IHC-Fr, IHC-P, IP, WB | |
Mouse, Rat | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
IHC, WB | |
Bovine, Canine, Equine, Goat, Guinea pig, Porcine, Rabbit, Rat | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
IHC, WB | |
Bovine, Canine, Equine, Goat, Porcine, Rabbit, Rat | |
Human | |
Rabbit | |
Polyclonal | |
Unconjugated |