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Catalog Number | orb2899215 |
---|---|
Category | Antibodies |
Description | CD194 is a G-protein-coupled seven membrane-spanning transmembrane protein serving as a high affinity receptor for C-C type chemokines TARC (CCL17) and MDC (CCL22), and as a coreceptor for HIV. It is expressed by all CLA+ T cells regardless of their Th1 or Th2 phenotype, on activated Th2, Treg, and activated NK cells, basophils and macrophages. Blocking CD194 function can be used for treatment of inflammation. |
Target | CD194 |
Clonality | Monoclonal |
Isotype | Mouse IgG1 |
Conjugation | Unconjugated |
Reactivity | Human |
Concentration | 1 mg/ml |
Buffer/Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
UniProt ID | P51679 |
Tested applications | FC |
Application notes | Flow cytometry: Recommended dilution: 0.5-4 μg/ml. |
Clone Number | rHIQB002 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Alternative names | CCR4, CC-CKR-4, CKR4, CMKBR4, ChemR13, HGCN |
Note | For research use only |
Entrez | 1233 |