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Catalog Number | orb749799 |
---|---|
Category | Antibodies |
Description | This mAb recognizes extracellular epitope of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis. |
Clonality | Monoclonal |
Species/Host | Mouse |
Isotype | Mouse IgG1, kappa |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant human protein was used as the immunogen for the CD147 antibody. |
UniProt ID | P35613 |
Tested applications | IHC-P |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
Application notes | Optimal dilution of the Emmprin antibody should be determined by the researcher. |
Antibody Type | Primary Antibody |
Clone Number | BSG/963 |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Hazard Information | This CD147 antibody is available for research use only. |
Note | For research use only |
IHC: Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with CD147 antibody (BSG/963).
IHC: Formalin-fixed, paraffin-embedded human colon carcinoma stained with CD147 antibody (BSG/963).
IHC: Formalin-fixed, paraffin-embedded human testicular carcinoma stained with CD147 antibody (BSG/963).
SDS-PAGE analysis of purified, BSA-free CD147 antibody (clone BSG/963) as confirmation of integrity and purity.
IHC-P, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
ELISA, IHC-P | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |