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CCR5 (M) Antibody, Rabbit Polyclonal
Catalog Number: orb67199
| Catalog Number | orb67199 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to CCR5.C-C chemokine receptor type 5 (CCR5) is a multi-pass membrane protein that belongs to the Gproteincoupled receptor 1 family. It is a receptor for a number of inflammatory CC-chemokinesincluding MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasingthe intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferationor differentiation. CCR5 acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.Genetic variation in CCR5 is associated with susceptibility to diabetes mellitus insulin-dependent type22 (IDDM22). |
| Clonality | Polyclonal |
| Species/Host | Rabbit |
| Conjugation | Unconjugated |
| Reactivity | Human, Mouse |
| Buffer/Preservatives | 0.01% NaN3 |
| Purity | Affinity purification |
| Immunogen | middle region of human CCR5 |
| UniProt ID | P51681 |
| MW | 41 |
| Tested applications | WB |
| Dilution range | WB:1:1000-1:3000 |
| Storage | -20°C |
| Alternative names | anti-CCR5 antibody,anti-CC chemokine receptor type Read more... |
| Note | For research use only |
Western blot analysis of total cell extracts from mouse brain using CCR5 antibody
