CCG-203971

SKU: orb1302967

Description

CCG-203971 is a non-cytotoxic inhibitor of serum response element (SRE) activation and cell migration in PC-3 prostate cancer cells. It demonstrates in vivo tolerability in mice and is a research tool for studying metastasis and Rho/MRTF/SRF signaling pathways.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1443437-74-8
• MW: 408.88
• Purity: 99.50%
• Formula: C₂₃H₂₁ClN₂O₃
• SMILES: Clc1ccc(NC(=O)C2CCCN(C2)C(=O)c2cccc(c2)-c2ccco2)cc1
• Target: Ras,Rho
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.89 mM);DMSO:50 mg/mL (122.29 mM)

Bioactivity

• Target IC50:
  SRE.L:0.64 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

migration, MKL1, PC-3, Inhibitor, MRTF, inhibit, CCG203971, CCG-203971, anti-metastasis, CCG 203971, Ras, Rho, SRF

Compound Identifiers

PubChem CID

71681561