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CCG-203971

SKU: orb1222695

Description

CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM), as determined by a scratch wound assay. CCG-203971 causes no cytotoxicity when evaluated by the WST-1 assay. It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days.

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Key Properties

CAS Number1443437-74-8
MW408.88
Purity>98% (HPLC)
FormulaC23H21ClN2O3
SMILESO=C(C1CN(C(C2=CC=CC(C3=CC=CO3)=C2)=O)CCC1)NC4=CC=C(Cl)C=C4
TargetDNA/RNA Synthesis
SolubilityDMSO : ≥ 155 mg/mL 379.08 mM; H2O : < 0.1 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CCG-203971 | CCG 203971

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    1443437-74-8

    408.88

    C23H21ClN2O3

    10 mg, 50 mg, 100 mg, 25 mg, 500 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

CCG-203971 (orb1222695)

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Available Sizes

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5 mg
$ 70.00
10 mg
$ 100.00
25 mg
$ 160.00
50 mg
$ 250.00
100 mg
$ 370.00
500 mg
$ 850.00