CC-90005

SKU: orb1694274

Description

CC-90005 is a potent, selective, and orally bioavailable inhibitor of protein kinase C-theta (PKC-θ), demonstrating an IC50 of 8 nM with significant selectivity over PKC-δ. It effectively suppresses T cell activation, as shown by the inhibition of IL-2 expression in vitro, making it a valuable tool for immunology and autoimmune disease research.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 1799574-70-1
• MW: 447.48
• Formula: C₂₁H₂₇F₂N₇O₂
• SMILES: CC(F)(F)COc1ncncc1CNc1ncc(C#N)c(N[C@@H]2CC[C@H](O)C(C)(C)C2)n1
• Target: Others,PKC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118162109