(1S,4R)-CC-90005

SKU: orb3210057

Description

(1S,4R)-CC-90005 is the (1S,4R)-enantiomer of CC-90005. CC-90005 functions as a potent, selective, and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 value of 8 nM. It exhibits significant selectivity for PKC-θ over PKC-δ (IC50 = 4440 nM). Additionally, CC-90005 can inhibit T cell activation by suppressing IL-2 expression.

Key Properties

• Target: PKC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PKC