CBS1117

SKU: orb1219241

Description

CBS1117 is an inhibitor virus entry inhibitor(IC50 of 70 nM for influenza A virus), A/Puerto Rico/8/34 (H1N1). It interferes with the hemagglutinin (HA)-mediated fusion process.CBS1117 which has a 50% inhibitory concentration of 70 nM and a selectivity index of ~4000 against A/Puerto Rico/8/34 (H1N1) infection in human lung epithelial cell line (A549).

Key Properties

• CAS Number: 959245-08-0
• MW: 315.24
• Purity: >98% (HPLC)
• Formula: C₁₅H₂₀Cl₂N₂O
• SMILES: O=C(NC1CCN(C(C)C)CC1)C2=C(Cl)C=CC=C2Cl
• Target: Influenza Virus
• Solubility: In Vitro: DMSO : 250 mg/mL (793.05 mM)

Bioactivity

• In Vitro:
  CBS1117 has a lower IC50 value of 70 nM and higher CC50 value of 274 μM, leading to an excellent antiviral selectivity index value (SI value of 3914) in human lung epithelial cell line (A549).
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Influenza Virus