CB2R/FAAH?modulator-2

SKU: orb2900633

Description

CB2R/FAAH modulator-2 (compound 26) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-2 are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.

Key Properties

• CAS Number: 2876918-68-0
• MW: 367.52
• Purity: >98% (HPLC)
• Formula: C₂₄H₃₃NO₂
• SMILES: N(C(=O)C1=C(OCC2CCCCC2)C=CC=C1)C34CC5CC(C3)CC(C4)C5
• Target: Cannabinoid Receptor

Bioactivity

• In Vitro:
  CB2R/FAAH modulator-2 (compound 26)(10 μM) reduces the production of the pro-inflammatory cytokines TNFα, IFN-γ, IL-1β and IL6 in unstimulated monocytes and macrophages.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Cannabinoid Receptor