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CB2 receptor agonist 8
Catalog Number: orb2814162
| Catalog Number | orb2814162 |
|---|---|
| Category | Small Molecules |
| Description | CB2 receptor agonist 8 (Compound 17) is an agonist of the cannabinoid receptor 2 (CB2 receptor). It shows cytotoxicity in U87, RPMI 8226, HL-60, and L929 cells with IC50 values of 91.03, 16.29, 23.51, and 564.6 μM, respectively. CB2 receptor agonist 8 activates caspase 3/7, increases the expression of pro-apoptotic genes BAX, BAD, BIM, and the tumor suppressor gene p53, and induces apoptosis in U87 cells. Additionally, it inhibits the migration of U87 cells. |
| MW | 395.47 |
| Formula | C23H26FN3O2 |
| Storage | -20°C |
| Note | For research use only |
AM251 [orb1225865]
> 98%(HPLC)
183232-66-8
555.2
C22H21Cl2IN4O
5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 g, 500 mg, 200 mg
