Cassiaside

SKU: orb1684716

Description

Cassiaside is a naphthyl ketone glycoside with BACE1 inhibitory activity (IC50=4.45 μM), relevant to Alzheimer's disease research. It has demonstrated hepatoprotective effects in models of galactosamine-induced injury, supporting its investigation in neuroprotection and liver disease studies.

Research Area

Neuroscience

Key Properties

• CAS Number: 13709-03-0
• MW: 420.37
• Purity: 98.00% (May vary between batches)
• Formula: C₂₀H₂₀O₁₀
• SMILES: O(C=1C2=C(C=C3C(=C2O)C(=O)C=C(C)O3)C=C(O)C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
• Target: Beta-Secretase,BACE
• Solubility: DMSO:20 mg/mL (47.58 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.76 mM)

Bioactivity

• Target IC50:
  BACE1:4.45 μM|BACE1:9.85 μM(Ki)

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BACE1, BChE, BetaSecretase, Beta-secretase, bSecretase, b-Secretase, Cassiaside, AChR, β-Secretase, βSecretase

Compound Identifiers

PubChem CID

135423317