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Cassiaside

SKU: orb1684716

Description

Cassiaside is a naphthyl ketone glycoside with BACE1 inhibitory activity (IC50=4.45 μM), relevant to Alzheimer's disease research. It has demonstrated hepatoprotective effects in models of galactosamine-induced injury, supporting its investigation in neuroprotection and liver disease studies.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number13709-03-0
MW420.37
Purity99.92%
FormulaC20H20O10
SMILESO(C=1C2=C(C=C3C(=C2O)C(=O)C=C(C)O3)C=C(O)C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
TargetBACE,Beta-Secretase
SolubilityDMSO:20 mg/mL (47.58 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.76 mM)

Bioactivity

Target IC50
BACE1:4.45 μM|BACE1:9.85 μM(Ki)

Storage & Handling

Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BACE1, BChE, BetaSecretase, Beta-secretase, bSecretase, b-Secretase, Cassiaside, AChR, β-Secretase, βSecretase

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Cassiaside (orb1684716)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 130.00
5 mg
$ 260.00
10 mg
$ 410.00
25 mg
$ 660.00