Cassiaside B2

SKU: orb1684717

Description

Cassiaside B2 is a bioactive naphthylpyrone that acts as a PTP1B and hMAO-A inhibitor, and a 5-HT2C receptor agonist. This multi-target profile suggests research applications in metabolic disorders, neurobiology, and allergy, as evidenced by in vitro studies on its anti-allergic mechanisms.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 218155-40-9
• MW: 920.82
• Purity: 99.88%
• Formula: C₃₉H₅₂O₂₅
• SMILES: O(C=1C2=C(C=C3C(=C2O)C(=O)C=C(C)O3)C=C(OC)C1)[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@@H](O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O)[C@H](O)[C@@H](CO)O5)[C@@H](O)[C@H](O)[C@H]4O
• Target: MAO,Phosphatase,Monoamine Oxidase,5-HT Receptor
• Solubility: DMSO:50 mg/mL (54.3 mM)

Bioactivity

• Target IC50:
  MAO-A:40.57 µM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cassiaside B2, Cassiaside B-2, 5HTReceptor, 5HT Receptor, 5-HT2C, MAO-A, PTP1B

Compound Identifiers

PubChem CID

10557731