Carboxyatractyloside

SKU: orb1299157

Description

Carboxyatractyloside is a natural compound that potently and specifically inhibits the mitochondrial ADP/ATP carrier (AAC), blocking nucleotide exchange. This inhibitor is widely used in biochemical research to study mitochondrial bioenergetics, apoptosis, and the role of the AAC in both cellular and isolated organelle experiments.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 77228-71-8
• MW: 770.82
• Purity: 99.83% (May vary between batches)
• Formula: C₃₁H₄₆O₁₈S₂
• SMILES: C[C@]12[C@]3([C@]4(C[C@@](CC3)(C(=C)[C@@H]4O)[H])CC[C@@]1(C(C(O)=O)(C(O)=O)C[C@@H](O[C@H]5[C@H](OC(CC(C)C)=O)[C@@H](OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@@H](CO)O5)C2)[H])[H]
• Target: Mitochondrial Metabolism,Others,Calcium Channel,ROS
• Solubility: DMSO:11 mg/mL (14.27 mM);H2O:262.5 mg/mL (340.55 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Carboxyatractyloside, Carboxyatractyloside tripotassium, Carboxyatractyloside tripotassium salt, Carboxyatractyloside tripotassium salt, C 4992, Gummiferin

Compound Identifiers

PubChem CID

20055804