Carbidopa

SKU: orb1300458

Description

Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29±2 μM. It is primarily used in Parkinson's disease research to mitigate the peripheral side effects of levodopa, enhancing its central nervous system bioavailability in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 28860-95-9
• MW: 226.23
• Purity: ≥98% (May vary between batches)
• Formula: C₁₀H₁₄N₂O₄
• SMILES: [C@@](CC1=CC(O)=C(O)C=C1)(C(O)=O)(NN)C
• Target: Aryl Hydrocarbon Receptor,Decarboxylase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.42 mM);DMSO:4.5 mg/mL (19.89 mM)

Bioactivity

• Target IC50:
  Aromatic-L-amino-acid decarboxylase:29 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Lodosyn, pancreatic, aromatic-L-amino-acid decarboxylase, Aryl Hydrocarbon Receptor, ArylHydrocarbonReceptor, Carbidopa, (S)-(-)-Carbidopa, AhR, peripheral

Compound Identifiers

PubChem CID

34359