Capsiate

SKU: orb3054613

Description

Capsiate is a non-pungent analogue of capsaicin with a similar biological profile. It has a role as an anti-allergic agent, a plant metabolite, an antioxidant, an angiogenesis inhibitor, a hypoglycemic agent, an anti-inflammatory agent and a capsaicin receptor agonist.

Key Properties

• CAS Number: 205687-01-0
• MW: 306.4
• Purity: >98% (HPLC)
• Formula: C₁₈H₂₆O₄
• SMILES: C(OC(CCCC/C=C/C(C)C)=O)C1=CC(OC)=C(O)C=C1
• Solubility: DMSO : 100 mg/mL (326.37 mM; ultraphonic; )

Bioactivity

• In Vivo:
  Capsiate does not exhibit irritancy-related effects on the oral cavity or eye. Capsiate (0.03~0.54 mM; s. c.) induces nociceptive responses in mice. Animal model: Male ddY-strain mice (20–24 g). Dosage: 0.5 or 5 mM. Administration: p.o. Result: Did not cause pungency-related behaviors.
• In Vitro:
  Capsiate evokes current responses in HEK293 cells expressing TRPV1.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only