Candidalysin

SKU: orb2563648

Description

Candidalysin is a cytolytic peptide toxin from Candida albicans that activates host epithelial EGFR signaling, triggering MMP activity, calcium influx, and inflammation. Its membrane-damaging cytotoxicity makes it a key tool for studying fungal pathogenesis, host-pathogen interactions, and innate immune responses in both in vitro and in vivo models.

Research Area

Cardiovascular Research, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Key Properties

• Target: MMP,Calcium Channel,EGFR
• CAS Number: 1906866-53-2
• MW: 3310.11
• Formula: C₁₅₃H₂₆₆N₃₈O₃₈S₂
• SMILES: C([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCSC)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)CC(N)=O)=O)[C@H](CC)C)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CC(N)=O)=O)=O)CCCCN)=O)=O)C)=O)CCCCN)=O)[C@@H](C)C)=O)[C@H](CC)C)=O)CO)=O)CCSC)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCC(N)=O)=O)[C@H](CC)C)=O)[C@@H](C)C)=O)CCC(N)=O)=O)CCC1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172653498