Calnexin Rabbit mAb [KD Validated] Antibody

SKU: orb1951410

Description

Calnexin is a calcium-binding protein embedded in the ER membrane that retains the newly synthesized glycoproteins inside the ER to ensure proper folding and quality control (3-5). The specificity of calnexin for a subset of glycoproteins is defined by a lectin site, which binds an early oligosaccharide intermediate on the folding glycoprotein.

Images & Validation

• Tested Applications: FC, ICC, IHC, WB
• Dilution Range: WB 1:1000~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 FC 1:100
• Reactivity: Human, Rat

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Calnexin
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Calnexin; CANX; CNX; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90;

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of Calnexin expression in HepG2 cell lysate.

Quick Database Links

UniProt

P27824