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Calbindin Antibody / CALB1

Catalog Number: orb1822850

DispatchUsually dispatched within 5-10 working days
$ 780.00
Catalog Numberorb1822850
CategoryAntibodies
DescriptionThe family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 Alpha and Beta, Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin Alpha and Parvalbumin Beta (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.
Species/HostMouse
ClonalityRecombinant
Clone NumberrCALB1/8499
Tested applicationsIHC-P
ReactivityHuman
IsotypeMouse IgG1, kappa
ImmunogenA recombinant partial protein sequence (within amino acids 7-96) from the human protein was used as the immunogen for the CALB1 antibody.
Antibody TypePrimary Antibody
Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
ConjugationUnconjugated
Formula1 mg/ml in 1X PBS; BSA free, sodium azide free
Hazard InformationThis CALB1 antibody is available for research use only.
UniProt IDP05937
StorageAliquot the CALB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
NoteFor research use only
Expiration Date12 months from date of receipt.
Calbindin Antibody / CALB1

IHC staining of FFPE human kidney tissue with CALB1 antibody (clone rCALB1/8499). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

Calbindin Antibody / CALB1

IHC staining of FFPE human kidney tissue with CALB1 antibody (clone rCALB1/8499). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

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