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CAL-130

SKU: orb1710173

Description

CAL-130 is a potent and selective dual inhibitor of phosphoinositide 3-kinase delta (PI3Kδ) and gamma (PI3Kγ) isoforms, exhibiting IC50 values of 1.3 nM and 6.1 nM, respectively. This small molecule is a valuable research tool for investigating PI3K signaling in immunological and oncological contexts, applicable in both in vitro cellular assays and in vivo disease models.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number1431697-74-3
MW426.47
FormulaC23H22N8O
SMILES[C@H](NC1=C2C(=NC(N)=N1)N=CN2)(C)C=3N(C(=O)C=4C(N3)=CC=CC4C)C5=C(C)C=CC=C5
TargetPI3K

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information