CAL-130 Hydrochloride

SKU: orb1710172

Description

CAL-130 Hydrochloride is a potent and selective dual inhibitor of phosphoinositide 3-kinase delta (PI3Kδ) and gamma (PI3Kγ) isoforms, exhibiting IC50 values of 1.3 nM and 6.1 nM, respectively. This small molecule is a valuable research tool for investigating the roles of these kinases in immunology and oncology, supporting both in vitro cellular assays and in vivo disease model studies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1431697-78-7
• MW: 462.94
• Formula: C₂₃H₂₃ClN₈O
• SMILES: Cl.C[C@H](Nc1nc(N)nc2[nH]cnc12)c1nc2cccc(C)c2c(=O)n1-c1ccccc1C
• Target: PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71576677