CADM1 Antibody (N-term)

SKU: orb28626

Description

Rabbit polyclonal antibody to CADM1 (also known as cell adhesion molecule 1, Nectin-like protein 2, synaptic cell adhesion molecule. IgSF4 and TSLC-1) is a tumor suppressor part of the immunoglobulin superfamily and has been found to show reduced expression in many different solid tumors. CADM1 has also been found to play a role in the formation of epithelia-like cell structure and also be important in psychiatric and behavioral disorders such as autism.

Research Area

Cancer Biology, Immunology & Inflammation, Neuroscience

Images & Validation

• Tested Applications: IHC-P, WB
• Dilution range: WB: 1:1000, IHC-P: 1:50-100
• Reactivity: Human, Mouse

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB22685
• Immunogen: Synthetic Peptide
• Target: CADM1
• Molecular Weight: 48509
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Disclaimer: For research use only

Alternative Names

anti-CADM1 antibody, anti-IGSF4 antibody, anti-IGSF4A antibody, anti-NECL2 antibody, anti-SYNCAM antibody, anti-TSLC1 antibody, anti-Cell adhesion molecule 1 antibody, anti-Immunoglobulin superfamily member 4 antibody, anti-Nectin-like protein 2 antibody, anti-Spermatogenic immunoglobulin superfamily antibody, anti-Synaptic cell adhesion molecule antibody, anti-Tumor suppressor in lung cancer 1 antibody

CADM1 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35 ug/lane). This demonstrates the CADM1 antibody detected the CADM1 protein (arrow).

CADM1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CADM1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

CADM1 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35 ug/lane). This demonstrates the CADM1 antibody detected the CADM1 protein (arrow).

Quick Database Links

Gene Symbol

CADM1

UniProt

Q9BY67

RefSeq (Protein):NP_001091987.1, NP_055148.3