c-JUN peptide

SKU: orb1679218

Description

This synthetic peptide corresponds to the JNK-binding δ domain (residues 33-57) of human c-Jun. It acts as a competitive inhibitor, disrupting the JNK/c-Jun interaction to block c-Jun phosphorylation and downstream signaling. This tool is applied in vitro to study JNK pathway inhibition, apoptosis induction in cancer cells like HeLa, and the modulation of p21 and inflammatory genes.

Research Area

Cancer Biology, Cell Biology, Signal Transduction

Key Properties

• Target: JNK,Apoptosis
• CAS Number: 610273-01-3
• MW: 2743.55
• Formula: C₁₂₁H₂₁₀N₃₆O₃₄S
• SMILES: C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)CO)=O)CCSC)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)C)=O)CC(O)=O)=O)CCC1)C(C)C)=O)=O)CO)=O)CC(C)C)=O)CCCCN)(=O)N2[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CCCCN)=O)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CCC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131855963