C 21

SKU: orb1679310

Description

This compound is a potent and selective inhibitor of protein arginine methyltransferase 1 (PRMT1), with an IC50 of 1.8 µM. It demonstrates significant selectivity over other PRMT family members. Such inhibitors are valuable tools for studying PRMT1's role in transcriptional regulation, splicing, and signal transduction in both cellular and animal models of cancer and other diseases.

Research Area

Epigenetics & Chromatin

Key Properties

• Target: Histone Methyltransferase
• CAS Number: 1229236-78-5
• MW: 2166.94
• Formula: C₉₀H₁₆₁ClN₃₆O₂₄
• SMILES: [C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC(CNC(CNC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC(C)=O)CO)=O)=O)CCCNC(CCl)=N)=O)=O)CCCCN)=O)=O)=O)CCCCN)=O)=O)CC(C)C)=O)=O)CCCCN)=O)=O)=O)C)=O)CCCCN)=O)CCCNC(=N)N)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46911727