Buspirone hydrochloride

SKU: orb1225273

Description

Buspirone hydrochloride is an anxiolytic psychotropic drug, is used to treat generalized anxiety disorder (GAD).(In Vitro):Buspirone hydrochloride (0-400 μg/mL; 6 hours) has cytotoxic effect in Lymphocytes. Buspirone hydrochloride (0-180 μg/mL; 0-3 hours; Lymphocytes) induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage and elevation of glutathione disulfide (GSSG).(In Vivo):Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) reduces anxiety/depression behaviors.Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) restores IS-shifted β-diversity in the gut microbiota.

Key Properties

• CAS Number: 33386-08-2
• MW: 421.96
• Purity: >98% (HPLC)
• Formula: C₂₁H₃₂ClN₅O₂
• SMILES: Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)C1=NC=CC=N1
• Target: 5-HT Receptor
• Solubility: Ethanol: 36 mg/mL (85.31 mM); Water: 84 mg/mL (199.07 mM); DMSO: 84 mg/mL (199.07 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MJ9022-1

Quick Database Links

Gene Symbol

5-HT Receptor