Birelentinib

SKU: orb2566759

Description

Birelentinib is a potent small molecule inhibitor of both wild-type and mutant Bruton's tyrosine kinase (BTK), exhibiting IC₅₀ values of 6.72 nM and 6.11 nM, respectively. It is a valuable research tool for studying B-cell signaling pathways in hematological malignancies, applicable in both in vitro biochemical assays and in vivo disease models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2662512-15-2
• MW: 453.44
• Purity: 99.78% (May vary between batches)
• Formula: C₂₃H₂₁F₂N₅O₃
• SMILES: NC=1C2=C(N=C(N2N=CN1)[C@@H]3CC[C@@H](CO)OC3)C4=CC=C(OC5=C(F)C(F)=CC=C5)C=C4
• Target: BTK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156565109