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BTK IN-1

SKU: orb1296114

Description

BTK IN-1 (SNS062 analog) is a potent small molecule inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 value below 100 nM. It serves as a valuable research tool for investigating BTK-dependent signaling pathways in both cellular and animal models of B-cell malignancies and autoimmune disorders.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1270014-40-8
MW384.86
Purity98.98% (May vary between batches)
FormulaC19H21ClN6O
SMILESClc1cccc(NCC(=O)NC2CCCN(C2)c2ncnc3[nH]ccc23)c1
TargetBTK
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6.5 mM);DMSO:95 mg/mL (246.84 mM);H2O:Insoluble

Bioactivity

Target IC50
BTK:<100 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, Bruton tyrosine kinase, Btk, BTK, BTK IN 1, BTK IN1, BTK IN-1, SNS 062, SNS062, SNS-062, SNS062 analog

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
2 mg
$ 90.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 160.00
25 mg
$ 230.00
50 mg
$ 370.00
100 mg
$ 510.00
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