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Bromodomain inhibitor-10

SKU: orb1688650

Description

Bromodomain inhibitor-10 (compound 128) is a potent, dual-bromodomain inhibitor with high affinity for BRD4-1 (Kd=15 nM) and BRD4-2 (Kd=2500 nM). It suppresses IL12p40 production and is a valuable chemical probe for epigenetic and inflammation research in cellular and biochemical assays.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1870849-58-3
MW364.4
FormulaC20H20N4O3
SMILESC(NC=1C=C2C(=CC1)NC(=O)C=C2C)(=O)C3=C(N=CC=C3)N4CCOCC4
TargetEpigenetic Reader Domain,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information