Brevianamide F

SKU: orb1225147

Description

A naturally occurring 2,5-diketopiperazine that possess interesting breast cancer resistance protein (BCRP) inhibitory activity.; also shows agonism towards Ca(2+)-channel activity at 100 uM, and has potentiation for use in the treatment of cardiovascular dysfunction.

Key Properties

• CAS Number: 38136-70-8
• MW: 283.3251
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₇N₃O₂
• SMILES: C1CC2C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43
• Target: BCRP
• Solubility: 10 mM in DMSO

Bioactivity

• In Vitro:
  Brevianamide F shows moderate activity against both MSSA and MRSA.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclo(L-Pro-L-Trp

Quick Database Links

Gene Symbol

BCRP