Brazikumab Antibody

• Catalog Number: orb1980510
• Category: Antibodies
• Description: Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit. It is a selective IL23p19 antagonist and can be used in Crohn's disease research.
• Clonality: Monoclonal
• CAS Number: 1610353-18-8
• Concentration: 5.98 mg/mL
• Purity: 95.00%
• Conjugation: Unconjugated
• Target: Brazikumab
• Biological Activity: Brazikumab (AMG 139), a human IgG2 monoclonal antibody, selectively targets the p19 subunit of IL-23 with a dissociation constant (K D) of 0.138 nM, indicating high affinity for human IL-23. It is employed in Crohn's disease research [1].
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.